Caithness Biotechnologies: Natural product libraries for drug discovery Harnessing Nature for drug discovery
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1) Advantages
2) Novelty
3) Rationale
4) Intellectual property
5) Unique molecules
6) Hit-rate
7) Diversity
8) Resupply
9) Unextracted herbs
10) Extraction
11) Ethnic data
12) Screening
13) Shelf-life
14) Kit sizes
15) Separation
16) Human studies
17) Pre-fractionation
18) 'Frequent hitters'


Natural product libraries for drug discovery


Frequently asked questions

05) How many unique molecules are contained in each extract of the library?

This question is much debated in the field, and a consensus answer is yet to emerge.

However, estimates of the average number of distinct compounds present within a crude plant extract range from hundreds to thousands [1].

The entire Phytotitre library may therefore contain thousands to hundreds of thousands of structurally distinct compounds - far greater than a synthetic compound library of equivalent size.

[1] Hostettmann K. Strategy for the Biological and Chemical Evaluation of Plant Extracts. IUPAC (1999)

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Natural product libraries for drug discovery


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