Caithness Biotechnologies: Natural product libraries for drug discovery Harnessing Nature for drug discovery
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1) Advantages
2) Novelty
3) Rationale
4) Intellectual property
5) Unique molecules
6) Hit-rate
7) Diversity
8) Resupply
9) Unextracted herbs
10) Extraction
11) Ethnic data
12) Screening
13) Shelf-life
14) Kit sizes
15) Separation
16) Human studies
17) Pre-fractionation
18) 'Frequent hitters'


Natural product libraries for drug discovery


Frequently asked questions

3) What is the rationale for the choice of species comprising the library?

The library has been designed to maximise potential content of molecules that may interact with pathways of interest, while minimising content of potentially toxic compounds.

Only plants with a history of oral or topical medicinal use in man, or a history of inverse association with risk of disease, are included (239 traditional medicines and 128 commonly consumed plants).
While some of the plants are well studied, others are poorly characterised, offering useful potential for the discovery of novel compounds.

The library has been sized to optimally balance accessibility and workflow for smaller research groups, together with sufficient representation of phytochemical diversity.

A list of all plants included in the library, together with notes on the rationale for the inclusion of each, based on either ethnopharmacological use and/or evidence of association with disease in epidemiological or interventional studies, is provided with all versions of the library (please click here to view a sample page).

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Natural product libraries for drug discovery


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