Caithness Biotechnologies Harnessing Nature for drug discovery


1) Advantages
2) Novelty
3) Rationale
4) Intellectual property
5) Unique molecules
6) Hit-rate
7) Diversity
8) Resupply
9) Unextracted herbs
10) Extraction
11) Ethnic data
12) Screening
13) Shelf-life
14) Kit sizes
15) Separation
16) Human studies
17) Pre-fractionation
18) 'Frequent hitters'


Frequently asked questions

18) Have you removed common problematic molecules from the extracts?

A number of common components of plant extracts, including saponins, tannins and fatty acids, have been reported to cause interference in some biological assays.

There is an argument for the pre-treatment of samples to remove such agents before library assembly.

However, this also results in the loss of many compounds with potentially useful activity.

To balance potential interference with compound diversity, the library has been pre-fractionated into one polar and one non-polar pre-fraction per extract without pre-treatment to remove major classes of phytochemicals.





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